Investigation and analysis on HPV infection status of 2 497 patients with gynecological disease in Chongqing

Abstract:

Objective:To investigate HPV infection status of women in Chongqing in order to provide theoretical basis for the prevention and treatment of the cervical cancer.Methods：The infection status of HPV in 2 497 outpatients of gynecology department was examined with gene chip technique in Chongqing Obstetric and Gynecology Hospital from May 2009 to November 2011.The infection status of various subtypes of HPV was compared and analyzed.Results：Among the 2 497 patients，432 patients were infected with HPV(17.30%)，and 274 patients were infected with HR-HPV(high risk HPV，10.97%).Out of the 23 subtypes of HPV，HPV-16 (32.18%，139/432)was the most common of all types，followed by subtypes HPV-43(18.75%，81/432)，HPV-58(15.05%，65/432)，HPV-52(13.19%，57/432)，HPV-6(8.56%，37/432)，and there was no HPV-44 or HPV-MM4.In the HPV positive patients，103(23.84%，103/432) patients were compound infected，of whom 82 (18.98%，82/432)patients were superinfected.The HPV positive rate in old women(≥50) was higher than that in the young crowd.Conclusion：It is important to detect and control HPV infection in order to prevent and treat cervical cancer.