Clinicopathological analysis of stomach glomus tumor in 6 cases

Abstract:

Objectve：To investigate the clinicopathological characteristics，differential diagnosis and prognosis of stomach glomus tu－mors. Methods：Totally 6 cases of stomach glomus tumors were studied by histopathological observation and immunohistochemical staining. Results：The study included 5 cases of benign tumors and 1 case of potential malignant stomach glomus tumor which was hard to predict. The tumor cells were uniform-sized，round or polygonel，arranged around the blood vessels. Immunohistochemical study demonstrated that tumor cells reacted positively to Vimentin，smooth muscle antibody（SMA），laminin，actin，but negatively to CD34，CD117，neuron specific enolase（NSE），AE1/AE3，CAM5.2 and carcino－embryonic antigen（CEA）. Conclusions：Stomach glo－mus tumor is rare and most of the time benign. It can be easily misdiagnosed by frozen section and clinical and cytological tests so that more attention should be paid on the disease and unnecessary surgical therapies should be reduced.