Complications of applying Angioseal arterial closure device versus and manual compression homeostasis after common femoral artery puncture in coronary intervention

Abstract:

Objective：To compare the safety between Angioseal closure device and manual compression homeostasis after performing coronary intervention through femoral artery puncture. Methods：Randomized double blind controlled trial was used. Totally 611 pa－tients treated with coronary intervention through femoral artery puncture from January 2008 to November 2011 were enrolled and di－vided into Angioseal closure device group and manual compression homeostasis group. Complications were compared between the two groups. Results：There was no difference in the overall complication rate between the two groups（P >0.05）. However，the compli－cation rate of Angioseal closure device group tended to increase at 24 h after the treatment（P<0.05）. Conclusions：Angioseal clo－sure device can not decrease complications because delayed complications may occur significantly after 24 h. Angioseal closure de－vice is not recommended to use after performing coronary intervention through femoral artery puncture.