Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age

Abstract:

Objective：To provide new ideas for forensic age estimation by studying relationship among cytochrome C oxidase（CCO）activity，contents of cytochrome C（Cyt C） in mitochondria of brain tissues and mice age. Methods：CCO activity and contents of Cyt C in mitochondria of brain tissues of 1，3，6，9，12 months old Kunming mice were detected using UV spectrophotometry. Results：CCO activity and contents of Cyt C in mitochondria of brain tissues were decreased gradually with the increase of mice age. Conclusion：CCO activity and contents of Cyt C in mitochondria of brain tissues may be used for age estimation.