Influences of different feeding ways on physical development of macrosomia：a prospective cohort study

Abstract:

Objective：To observe the influences of different feeding ways on physical development and nutritional status of macrosomia. Methods：Totally 377 macrosomia were recruited from Chongqing Maternal and Child Care Service Ｃentre and the Children’s Hospital of Chongqing Medical University as subjects in this cohort study including 155 in pure breastfeeding group，142 in partial breastfeeding group and 80 in artificial feeding group. In follow-up tracking，the weights and lengths were measured when the macrosomia at postna－tal 1-6，8，10，12 months old. Changes of weight for age Z score（WAZ） between delivery and at 12 months old was used to evaluate the growth rate；weight for length Z score（WLZ） was used to evaluate their nutritional status. Results：Weight of macrosomias was sig－nificantly lower in pure breastfeeding group than in other two groups when at 10 months old and 12 months old（10 months old：F=4.015，P=0.021；12 months old：F=5.093，P=0.008）. There was no significant difference in length of macrosomias among three feeding groups. Growth velocities in three feeding groups were in negative growth and there was no significant difference among them. There was no significant difference in overweight incidence among three feeding groups. Conclusions：Growth rate of macrosomia within 1 year is decreased. Pure breastfeeding as the main feeding pattern can improve the macrosomia’s physical development. In addition，par－tial breastfeeding and formula feeding may potentially trigger the occurrence of obesity.