Correlation between serum vitamin A and blood lipid among middle-to-old-aged population in gerocomium of Chongqing

Abstract:

Objective：To study the correlation between serum vitamin A（VA） and blood lipid triglyceride（TG），total cholesterol（TC），low density lipoprotein（LDL），high density lipoprotein（HDL） by researching the levels of VA and lipid among people aged 50 years old or more in gerocomium of Chongqing and to explore the possibly mechanism between VA and lipid. Methods：A total of 480 peo－ple meeting the inclusion criteria were randomly recruited from 12 gerocomiums of Chongqing. Serum VA and blood lipid were mea－sured by high performance liquid chromatography and Siemens 2400 biochemical detector，respectively and their correlation was ana－lyzed. Results：Serum VA was negatively correlated with LDL significantly（β=-0.068，P=0.017） and was not correlated with TC and HDL. There was significant correlation between serum VA and TG（β=-0.338，P＝0.000）. The most significant correlation between serum VA and LDL was seen in 70-80 years old（β=-0.136，P=0.005），and VA was a protective factor for the prevalence of high LDL（OR=0.286，95%CI＝0.110－0.747）. Conclusions：VA is significantly correlated with LDL but not with HDL and TC in gerocomium of Chongqing. The most significant correlation between serum VA and LDL is seen in 70-80 years old group. There is significant corre－lation between VA and TG，the mechanism of which should be studied further.