MicroRNA-21 in organ fibrosis

Abstract:

Organ fibrosis is acute or chronic pathological changes caused by a variety of factors. Lack of effective treatment will even－tually lead to organ failure. In recent years，the study of microRNA receives more and more attention. Especially microRNA-21，as a small molecule regulating RNA，plays an important role in the occurrence of a variety of diseases，including cancer，cardiovascular disease，organ fibrosis. This paper reviewed microRNA-21 in various fibrotic diseases.