Association between atrial fibrillation and atrial ion channels remodeling induced by aging

Abstract:

Atrial fibrillation（AF） is one of the most common clinical tachyarrhythmia，which is seen most frequently in the elderly. Ag－ing is regarded as an important risk factor for AF. A lot of researchers find that atrial remodeling plays an important role in occurrence and maintenance of the age-related AF. The changes of ion channel currents and its channel protein or gene expression in atrial my－ocytes are related to occurrence of atrial remodeling. This paper made a review on the recent studies of the relationship between AF and the changes which leaded by aging in atrial remodeling and ion channels.