Evaluation of type 2 diabetes with peripheral atherosclerosis by using echo-tracking

Abstract:

Objective：To apply the echo-tracking（ET） to evaluate the peripheral artery function，to explore the influencing factors of detecting parameters of patients with type 2 diabetes and to provide scientific basis for early clinical prevention and treatment of dia－betic patients with peripheral vascular disease. Methods：Totally 128 patients with type 2 diabetes were taken as diabetic group and 120 health volunteers were recruited as control group in this study. ET technology was used to detect pressure-strain elasticity coeffi－cients（Ep），stiffness parameter β（SPβ），arterial compliance（AC），pulse wave velocity β （PWVβ），augmentation index（AI） and sys－tolic diameter（Ds），diastolic diameter（Dd） and intima media thickness（IMT） both in diabetic group and control group. Vascular function in the carotid，femoral and brachial artery was quantitatively evaluated and influencing factors of ET were analyzed by using basic information of the cases. Results：Values of Ep，SPβ and PWVβ in the arotid，femoral and brachial artery in diabetes group were significantly higher than those in controls（P<0.05）. AC values in the arotid，femoral artery were significantly lower in diabetes group than in control group（P<0.05）. Among the factors of age，duration of diabetes，fasting glucose，2 h postprandial blood glucose，triglycerides，total cholesterol and other factors，the main influencing factors were age，duration and total cholesterol. Ep，SPβ and PWVβ were positively correlated with age and diabetes duration（P<0.05）. AC values were negatively related with age and duration（P<0.05） but were positively correlated with total cholesterol（P<0.05）. Also，AI values were positively correlated with age（P<0.05）. Conclusion：ET can be used for the evaluation of type 2 diabetes patients with peripheral atherosclerosis，and the main influencing factors of its detection indicators are age and disease duration. This method can accurately evaluate the functional or pathological changes in type 2 diabetes patients with peripheral atherosclerosis and it is of great significance for early prevention and treatment of the diabetes.