Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review

Abstract:

Objective：To systematically review the clinical efficacy of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction（STEMI）. Methods：Literature search was performed among Pubmed，CNKI，VIP，Wangfang databases to search for available randomized control trials comparing aspiration thrombectomy combined with percutaneous coronary intervention（PCI） and single PCI. The Meta-analysis was conducted by using RevMan 5.2 software. Results：Totally 13 trials concerning 11 823 patients were enrolled. There was no statistically significant difference in all-cause mortality between aspiration thrombectomy combined with PCI and single PCI（RR=0.85，95%CI=0.73 to 1.00，P=0.05）. Major adverse cardiac events（MACE） was significantly reduced in aspira－tion thrombectomy combined with PCI than in single PCI（RR=0.81，95%CI=0.68 to 0.97，P=0.02）. Conclusion：Aspiration thrombec－tomy is conducive to reducing MACE.