A systematic review of Chinese herbal gastrointestinal intubation in patients with Ileus

Abstract:

Objective：To evaluate the effectiveness of Chinese herbal gastrointestinal intubation in the treatment of patients with ileus . Methods：Electronic databases such as PubMed，Web of Science，EMbase，EBSCO，the Cochrane Library，CNKI，WanFang，VIP and CBM were searched from their establishment to July 2014 to meet the inclusion criteria of randomized controlled trials（RCTs） and quasi-randomized trials（quasi-RCTs）. Meta analysis was conducted using RevMan 5.3 and Stata 12.0 software. Results：A total of 35 RCTs or quasi-RCTs involving 3 234 patients were included. The results of Meta analyses showed that the Chinese herbal gastrointesti－nal intubation group was superior to control group in raising the total clinical effective rate（Dachengqi decoction group：RR=1.21，95%CI=1.16 to 1.25，P=0.000；other decoction group：RR=1.23，95%CI=1.16 to 1.31，P=0.000） and the cure rate（Dachengqi decoc－tion group：RR=1.25，95%CI=1.14 to 1.36，P=0.000；other decoction group：RR=1.38，95%CI=1.24 to 1.52，P=0.000） as well as in shortening the hospitalization time（WMD=-4.27，95%CI=-5.95 to 2.60，P=0.000），restoring anus exhausting time（WMD=-6.67，95%CI=-11.74 to 1.60，P=0.001），restoring defecating time（WMD=-13.29，95%CI=-20.75 to -5.84，P=0.001） and disappear time of bowel sound（WMD=-1.28，95%CI=-1.69 to 1.03，P=0.000），with statistical differences. Conclusion：Chinese herbal gastrointestinal in－tubation treatment is superior to basic Western medicine for ileus. Due to limitations to quality of included studies，this conclusion has yet to be carried out in large multicenter study to validate.