Several methods have been established for measuring coronary flow reserve（CFR）. Transthoracic Doppler echocardiography（TDE） is a very useful method. TDE-CFR measurement is helpful in functional assessment of moderate stenosis，and can be used for assessment of acute coronary syndrome and myocardial infarction，as well as for monitoring of restenosis after revascularization. While in the absence of stenosis in the epicardial coronary artery，CFR can assess coronary microcirculation. Combined assessment of CFR and wall motion analysis can significantly improve the diagnosis values of coronary microcirculation disease. TDE-CFR is widely used in anterior descending artery. With the advances of the technology，the success rate of detection in circumflex and right coronary artery is increasing.

Abstract:

coronary heart disease；coronary flow reserve；transthoracic echocardiography