Clinical analysis of common inhaled allergens in 6 197 children with allergic rhinitis in Chongqing

Abstract:

Objective：To investigate the distribution characteristics of inhaled allergens and its influencing factors in children with al－lergic rhinitis（AR） in Chongqing. Methods：All cases were collected from otorhinolaryngological department of the Children’s Hos－pital of Chongqing Medical University from 1st January，2006 to 29th April，2012. Totally 6 197 children with allergic rhinitis from 4 months to 12 years old in Chongqing urban districts were enrolled. All the patients underwent skin prick test（SPT） with 13 standard－ized common inhalant allergens. The correlation between the positive rates，grades，categories of allergens and gender，age，living en－vironment was analyzed. Results：①Of the 6 197 AR patients，4 048（65.32%） were atopic；dermatophagoides pteronyssinus（65.06%），dermatophagus farinae（63.35%） and blomia tropicalis（40.07%） were the top three prevalent inhalant allergens. ②From 2006 to 2012，the SPT positive rate increased sharply，then tended to be stable，and then decreased slowly（50.64%，80.21%，81.20%，82.36%，77.34%，71.18%，56.01%）. ③With the growth of age，the positive rates，grades and categories of SPT increased，and the preponderance of atopy in boys was more significant. ④In the male infancy and preschool children with AR，the SPT positive rate of central downtown patients was significantly increased compared with those in the suburbs. Conclusion：Dermatophagoides ptero-nyssinus，derma-tophagus farinae and blomia tropicalis are the most prevalent in－halant allergens in AR disease in Chongqing urban districts. With the growth of age，children with allergic rhinitis，espe－cially boys，are more susceptible to inhalant allergens.