Study of event-related potentials of non-treatment major depressive disorder patients with suicidal ideation

Abstract:

Objective：To explore the characteristics of event-related potential of MDD（major depressive disorder） patients with suici－dal ideation. Methods：We collected MDD patients with suicidal ideation by certain inclusive and exclusive criterias in Mental Health Center，the First Affiliated Hospital of Chongqing Medical University，and recorded the event-related potent（ERP） of 20 non-treatment MDD patients with suicidal ideation when executing emotional stroop mission. Results：The total average reaction time of MDD patients with suicidal ideation was （695.04±2.16） ms；the reaction time was statistical significant between the different word-facial tasks（P<0.05）；there is no statistical significance in the latentperiodofERP related components：P1，N1，P2，P3 of MDD patients with suicidal ideation under four words-facial interference.There were statistical significancesin the amplitude of ERP related components：N1，P2，P3，which under four words-facial interference. Conclusion：Attentional bias and cognitive function differences existed in different emotional-facial stimulus for MDD patients with suici－dal ideation.