Protective effects of sevoflurane on myocardial ischemia reperfusion injury

Abstract:

Large amounts of experiments have proved that sevoflurane，both preconditioning and post-conditioning，has the cardio-protective effect. However，the specific mechanism of this effect has been studied a lot and is greatly disputed. This article reviews these mechanisms in the cardio-protective effect of sevoflurane. Meanwhile，theoretical bases for rational administration of sevoflurane during clinical anesthesia are provided. The application and its limitations of the cardio-protective effect of sevoflurane in the current clinical work，along with our expectations are also put forward.