Overview of progress and clinical application in gene sequencing technology

Abstract:

Gene sequence technology has rapidly developed with the concept of ‘precise medical treatment’ in recent years. It explains the classical concepts of genetics，developmental biology，evolutionary biology and other disciplines from the perspective of genomic mechanisms. New concepts such as high-order chromosome conformation，cellular heterogeneity，and functional modules are extended at the genome level by it，which also opens up new fields of application for precision medicine.