Influence of high body mass index on early complications after thoracoscopy and laparoscopy assisted radical surgery of esophageal carcinoma

Abstract:

Objective：To investigate the influence of high body mass index（BMI） on early complications after thoracoscopy and la－paroscopy assisted radical surgery of esophageal carcinoma. Methods：The clinical data of 186 patients with esophageal cancer under－going the thoracoscopy and laparoscopy assisted radical surgery between July 2014 and July 2017 in Department of Cardiothoracic Surgery，First Affiliated Hospital of Chongqing Medical University were collected and retrospectively analyzed. Patients with preopera－tive adjuvant radio-chemotherapy treatment，basic cardiopulmonary diseases and diabetes，hypoalbuminema（albumin<35 g/L），low BMI（BMI＜18.5 kg/m2） and poor pulmonary function（FEV1/FVC<70%） were excluded. Finally 139 patients met the eligibility crite－ria. The 139 patients were divided into normal BMI group（18.5 kg/m2≤BMI＜24 kg/m2，n=96） and high BMI group（BMI≥24 kg/m2，n=43）. Then the operation time and the prevalence of postoperative complications were compared. Results：There was no statistical difference in the operation time between the two groups（t=-1.910，P=0.0583）.The prevalence of incision infection in high BMI group was significantly higher than that of normal BMI group（22.86% vs. 7.87%， χ2=3.948，P<0.05）. However no significant difference was found between these 2 groups in the incidence rates of anastomotic leakage，pulmonary complications，cardiac complications and chy－lothorax（ χ2=0.026， χ2=0.033， χ2=0.598， χ2=0.008，P>0.05 for all）. Conclusion：Patients with higher BMI are more likely to have inci－sion infection.