Research progress of cell membrane biomimetic nanomaterial in tumor targeted therapy

Abstract:

Cell membrane biomimetic nanomaterial is a new type of probe. Nanoparticles can bind to tumor cells through enhanced permeability and retention（EPR） effect by passive targeting and recognize specific molecular typing of tumor cells by active target－ing，which turns tumor therapy from tissue and organ level to molecular level. At the same time，the cell membrane biomimetic nanoparticles can significantly prolong the targeting ability and circulation time of traditional nanoparticles，and thus enhance the therapeutic effect obviously. Therefore，it has shown unique advantages in the precise treatment of tumor targeting. In this paper，the latest development of several typical biomimetic nanoscale probes in tumor targeting therapy is reviewed.