Visualization research on mechanism of type 2 diabetes mellitus based on mapping knowledge domain

Abstract:

Objective：To analyze the development process of pathogenesis of type 2 diabetes mellitus（T2DM） and its research hotspots and frontiers of research. Methods：The web of science was searched for articles published during 2008-2015 and studies related to the pathogenesis of T2DM were selected. Data were analyzed by CiteSpasce Ⅲ. Results：In recent years，study on pathogenesis of T2DM shows a developing trend obviously. Core academic groups are mainly distributed in the United States，China，Japan，England，Germany and other countries with high prevalence. Focus of the study revolves around insulin resistance and islet cell function dis－order，including genetic susceptibility，obesity，inflammation，gut microbiota disruption，and diabetes complications. Conclusion：In countries with high prevalence of T2DM，the mechanism research have been attached great importance. And in recently，the insulin resistance induced by different pathways is the core content in the fields of mechanism study.