Pulmonary nocardiosis：2 case reports and literature review

Abstract:

Objective：To investigate the clinical features of pulmonary nocardiosis. Methods：The complete clinical data of two cases of pulmonary nocardiosis were analyzed from the clinical features and treatment，clues for early clinical diagnosis were provided. Results：One patient had chronic lung disease，the other patient with dermatomyositis and received long-term steroid and immunosuppressive therapy. They had the risk of infection with the pulmonary nocardia. Their early symptoms were fever，cough，positive body fluid culture for more than 5 days. One case died，and one case was once relieved，but died due to the merger of tuberculosis and intracranial infec－tion. Conclusion：Clinical features and imaging findings of pulmonary nocardiosis are nonspecific. Prolonged fluid incubation time over 5 days may generate a positive result. Early combined treatment may reduce the mortality rate，but the non symptom of intracranial infection should be alerted.