Efficacy of carboxymethylcellulose sodium eye drops in the management of dry eyes after phacoemulsification for diabetic cataract patients

Abstract:

Objective：To investigate the effect of carboxymethylcellulose sodium eye drops on the diabetic cataract patients with dry eye after phacoemulsification. Methods：A total of 117 patients underwent operation（151 eyes） with diabetic cataract referred to our hospital from June 2015 to June 2016 were enrolled in the study. Patients were randomly divided the control group（61 patients，84 eyes） and treatment group（56 patients，67 eyes）. The routine antibiotic and anti-inflammatory eye drops were used in control group，while treatment group was received carboxymethylcellulose sodium eye drops therapy except the routine treatment. Tear break-up time，Schimer I test，cornea fluorescein staining were measured，as well as subjective symptoms were graded before and on 1 day，at 1 week，1 month and 2 months after phacoemulsification and intraocular lens implantation. Results：All the subjective symptoms were worse，tear break-up time was shorter，S I t was prolonged and cornea fluorescein staining on epithelium was more commonly seen post-operation as compare to pre-operation（P<0.05）. The subjective symptoms grade and tear break-up time were still worse than the conditions that before operation in the control group 2 months post-operation（P<0.05）. However，the subjective symptoms grade，tear break-up time and cornea fluorescein staining on epithelium 1 month post-operation was similar to that pre-operation conditions（P>0.05），and all the post-opertation index were better in the treatment group than that in control group（P<0.05）. Conclusion：The carboxymethylcellulose sodium eye drops could efficiently relieve the symptoms of dry eye and maintain the tear film stable for the diabetic cataract patients underwent phacoemulsification.