Abstract:Dementia remains an incurable disease at present and has brought heavy social burden which is increasing year by year. Patients with dementia and their caregivers are always faced with a lot of physical and psychological needs in the end stage of life. Therefore, treatment for patients with advanced dementia should focus on the prevention and alleviation of pain, so as to improve their quality of life. Effective palliative treatment of patients with advanced dementia and appropriate medical decisions, which meet the needs of patients and their families, can improve their symptoms, increase the degree of comfort, and reduce the burden of caregivers. This article reviews the research advances in medical decision-making for patients with advanced dementia.