Molecular biology advances in amyotrophic lateral sclerosis

Abstract:

The pathogenesis of amyotrophic lateral sclerosis (ALS) remains unclear. Multiple genetic factors contribute to the degeneration of motor neurons and thus increase the susceptibility to ALS. With the rapid development of molecular biology techniques in recent years, there is an increasing diversity of research topics on ALS pathogenesis. Therefore, this article will illustrate the possible pathogenesis of ALS with reference to the latest achievements in the field of molecular biology and our own perspectives.