Abstract:Human brain banks collect postmortem and resected human nervous tissue samples and data on diseases and lifestyle before death from donors and thus support the observation and research on healthy or diseased human brain tissue. The establishment of human brain banks has been taken seriously in Western developed countries, with the formation of large-scale brain banks focusing on clinical cohorts. Human brain banks promote the exploration of human brain morphology and function, neurodevelopment and aging, and pathogenesis and mechanism of various neurological and mental disorders, gradually reveal the mechanism of normal brain activities, and thus provide new directions for the prevention and treatment of nervous system diseases. Human brain banking needs to be promoted in China. This article introduces the significance of human brain banking and the basic information of human brain banks in foreign countries, as well as investigations and reflections of the current status of human brain banking in China.