Effect of radiotherapy on ovarian function after ovarian transposition in patients with cervical cancer

Abstract:

Objective：To investigate the effect of radiotherapy on ovarian function in patients with cervical carcinoma after ovarian transposition. Methods：Data of 51 patients with stage Ⅰ-Ⅲ cervical carcinoma undergoing ovarian transposition and radiotherapy in our hospital from 2015 to 2019 were collected. Among those patients，5 patients showed progression and 5 patients lost follow-up. The postoperative condition were followed up，the modified Perimenopausal Syndrome Scale（modified Kupperman scale） was used to give score，and ovarian dysfunction and sexual life were observed. Results：Grouping based on age（≥ 40 years old and < 40 years old），operative way（radical laparotomy，laparoscopic radical operation and laparoscopic staging） and postoperative time（≥1 year and < 1 year） showed there was no statistical significance between ovarian dysfunction and age，as well as postoperative time. There were no significant differences in postoperative ovarian dysfunction between radical laparotomy and laparoscopic radical operation，as well as laparoscopic radical operation and laparoscopic staging（P<0.05）. A few patients（18%） had sexual life，and a very few patients（6%） were satisfied with sexual life. Conclusion：The change of ovarian function after ovarian transposition is not related with age and post－operative time，but may be related with operative ways. The preservation of ovarian function after ovarian transposition is very impor－tant for the life quality of young patients.