Advances in laser capture microdissection and its clinical application

Abstract:

Laser capture microdissection（LCM） technique can accurately separate a single type of cells or a single cell from complex tissue samples. It is a common tool for studying the specific expression of tissue or cells and their molecular mechanism and is an indispensable technique in the field of life sciences in the 21st century. At present，LCM has been widely used in the research on is－chemic cerebrovascular diseases. This article describes the principle，classification，development，application，and perspectives of LCM and analyzes the application of LCM in cerebral ischemia.