Comparison of clinical data of COVID-19 patients with different nutritional risk and the correlation between nutrion and clinical classifications

Abstract:

Objective：To investigate the differences in clinical data of coronavirus disease 2019（COVID-19） patients with different nutritional risks and the correlation between nutrition and clinical classifications through nutritional risk screening 2002（NRS２００２）. Methods：A total of 241 patients admitted to Chongqing Three Gorges Central Hospital from January 24th，2020 to February 29th，2020 were included in this research. Clinical classifications were defined according to the sixth edition of the “diagnosis and treatment plan of novel coronavirus pneumonia” promulgate by the National Health Commission of China，and all patients were divided into the nutritional risk group（NRS２００２ score≥3） and the non-nutritional risk group（NRS２００２ score<3）. The difference of age，gender，basic diseases，laboratory indexes and clinical classifications were compared in these groups. The correlation between the NRS２００２ score and clinical classifications were analyzed. The risk factors of clinical classifications were analyzed by multiple ordinal logistic regression. Results：The patients in the nutritional risk group were older（P=0.000），and there were more patients with COPD（P=0.023） and diabetes（P=0.000） in this group. However，the oxygen partial pressure（P=0.038），lymphocyte counts（P=0.000）and serum albumin（P=0.000） were lower than those of the non-nutritional risk group. The correlation analysis between NRS２００２ scores and clinical classifications suggested a positive correlation between them（r=0.635）. NRS２００２ score was an independent risk factor of clinical classifications（OR=6.841，P=0.000）. Conclusion：Nutrional risk score is an independent predictor of the clinical classifications of COVID-19 patients. NRS２００２ can be used in the evaluation and screening of COVID-19 patients，and it can be used to guide in-hospital triage and nutritional therapy simply and rapidly.