High resolution CT manefestation and pulmonary inflammation index of COVID-19 as well as their clinical correlation

Abstract:

Objective：To analyze the high resolution CT（HRCT） imaging manifestations of coronavirus disease 2019（COVID-19） and to investigate the correlation between CT pulmonary inflammation index（PII） and multiple clinical laboratory indexes. Methods： HRCT imaging of 57 patients with COVID-19 admitted to our hospital from January 2020 to February 2020 in our hospital were retrospectively analyzed，CT pulmonary inflammation index was calculated，and the correlation of CT pulmonary inflammation index with patients’ age，erythrocyte sedimentation tate（ESR），C-reactive protein（CRP），interleukin 6（IL-6），lymphocyte count（LYM） and oxygenation index（OI） was analyzed. Results：There were 3 patients with negative pulmonary examination and 54 patients with posi－tive lung lesions. HRCT showed 8 patients in early stage，45 patients in advanced stage，1 patient in remission stage，1 patient with bilateral small amount of pleural effusion，1 patient with bronchiectasis，3 patients with tuberculosis，7 patients with calcification of aortic wall or（and） coronary artery wall，and 5 patients with emphysema. CT PPI was positively correlated with age，ESR，CRP and IL-6（P<0.05）；was negatively correlated with Lym and OI（P<0.05）. Conclusion：HRCT manifestations of COVID-19 have certain characteristics. CT PPI is correlated with multiple clinical laboratory indexes，and can be used as a means of semi-quantitative assessment of COVID-19 lung injury.