Formation mechanism and resistance study of Candida tropicalis biofilm

Abstract:

Candida tropicalis has become the third most common fungal pathogen，and its ability to form biofilms is considered as one of the most important virulence factors. The biofilm of Candida tropicalis is an independent risk factor for high morbidity and mortality in inpatients，and is associated with poor prognosis in infected patients. However，studies on Candida tropicalis biofilms are rare and scattered. For this reason，this paper will provide a systematic and comprehensive review of Candida tropicalis in terms of environmental factors，gene regulation，resistance，and resistance mechanisms.