Advances in molecular biology of acupuncture on treating alzheimer’s disease

Abstract:

With the aggravation of population aging，Alzheimer’s disease（AD），as an irreversible neurodegenerative disease，plagues people all over the world and brings a heavy burden to families and the society. Acupuncture plays an increasingly important role in the clinical treatment of AD with its advantages of safety，simplicity and good effect. This paper summarizes the molecular biology researches of acupuncture in the treatment of AD in the past five years and also concludes the treatment effects of acupuncture on AD achieved by regulating the level of abnormal proteins，regulating the central cholinergic system，protecting neurons，regulating energy metabolism，inhibiting inflammatory response，and increasing the level of autophagic activity. That provides a theoretical basis for the clinical application of acupuncture in the treatment of AD.