Endocrine therapy in hormone receptor positive breast cancer

Abstract:

Breast cancer is one of the most common malignant tumors in Chinese women，and is a hormone dependent tumor. In recent years，endocrine hormone pathway drugs for breast cancer have been developed and applied，and some of them have been demonstrated that can improve the prognosis，achieving good clinical results in breast cancer patients. The treatment plan for breast cancer patients is changing rapidly and endocrine hormone therapy has become the first-line treatment for the hormone receptor positive patients in breast cancer. This study has reviewed the mechanism，side effects，drug resistance and ongoing clinical research of endocrine hormone therapy in breast cancer patients.