Clinical efficacy of endoscopic gastric variceal ligation vs. gastric variceal obliteration in treating type 1 gastroesophageal varices bleeding

Abstract:

Objective：To evaluate the clinical efficacy and safety of gastric variceal ligation（GVL） vs. gastric variceal obliteration（GVO） in controlling type 1 gastroesophageal varices（GOV1） bleeding. Methods：The clinical data of patients with GOV1 gastric variceal bleeding were analyzed retrospectively，including 61 cases treated with GVL（GVL group） and 69 cases treated with GVO（GVO group）. The hemostatic success rate，gastric variceal（GV）eradication rate，rebleeding rate and complications incidence were compared between GVO and GVL treatment groups. Results：Both GVO and GVL treatment groups were effective in controlling acute GV hemor－rhage and had the similar hemostasis rate，98.04% in GVO group and 100.00% in GVL group，without significant differences（P=1.000）. During the follow-up period，23.19% of GVO patients experienced rebleeding，compared with 16.39% rebleeding rate in GVL-treated patients，but the rebleeding rates were not significantly different between the two groups（P=0.334）. 50.72% of patients treated with GVO and 52.46% of patients treated with GVL were found gastric varices reduction or eradication，with no significant difference between two groups（P=0.756）. The incidence of complications in GVL group were 16.39%，whereas 40.58% of patients were found with complications in GVO group，with significant differences between the two groups（P=0.004）. Conclusion：Our results show that GVL and GVO are both effective in controlling gastric variceal bleeding and rebleeding，but the complications incidence of GVL is lower than that of GVO.