Abstract:As one of the most common neurological diseases in the world, epilepsy has numerous neurobiological, cognitive and psychosocial consequences. Timely diagnosis of epilepsy and appropriate treatment is of great significance to improve patient outcomes. As science and technology advances, diagnosis of epilepsy is being increasingly improved. This article will start with aspects of neuroimaging, nerve electrophysiology, genetics, body fluid examination, neuropsychology, immunology and artificial intelligence, review advances in the diagnosis of epilepsy and look forward to the future. We are trying to explain the status and progress of clinical diagnosis of epilepsy.