Progresses in diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy

Abstract:

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common chronic immune-mediated peripheral neuropathy. Early and accurate diagnosis is crucial for treatment and prevention of irreversible nerve damage. This article reviews recent progresses in clinical types, diagnosis and treatment of CIDP. The discovery of specific IgG4 antibodies against nodal and paranodal proteins, as well as nerve/nerve root enlargement revealed by nerve ultrasound and MRI, could be effective supplemental tools for diagnosis.