Abstract:Headache is one of the most common clinical complaints, with complex clinical manifestations and diverse causes. Correct clinical reasoning and methods are very important. Therefore, it is necessary to grasp the diagnostic classification of headaches and identify the clinical characteristics of common headache diseases. Firstly, a detailed medical history inquiry is required to understand the nature and type of headache, duration, accompanying symptoms and related medical history in clinical practice. Secondly, relevant physical examinations and targeted auxiliary examinations should be carried out, and indiscriminate auxiliary examinations can’t contribute to diagnosis. Based on the above process, the etiological diagnosis of different headache diseases can be completed. This article intends to combine the diagnostic criteria of The International Classification of Headache Disorders, 3rd Edition to explain how to make a diagnosis of headache diseases through medical history inquiry, physical examination and auxiliary examinations.