Abstract:Objective: To study the neuropsychological performance of the elderly with reversible cognitive frailty (RCF), and to compare the differences among them and the normal, the single subjective cognitive decline (SCD) and the single frailty. Methods: The study selected 166 elderly people aged≥60 years old and without obvious cognitive impairments in the clinic of Fuxing Hospital Affiliated to Capital Medical University and its surrounding communities from January 2015 to June 2018.Demographic and general clinical data of the elderly were collected, and the frailty or cognitive function of them were assessed. They were divided into four groups: normal control, single SCD, single frailty and RCF. The neuropsychological performances between different groups were studied. Results: From normal to RCF, the scores of memory and language function-related tests of the four groups were reduced in turn. Between the RCF and the normal control group, the immediate recall (P=0.036) and short delay recall (P=0.020) of the auditory vocabulary learning test (P=0.032), and the animal-household products alternating fluency test (P=0.011) were statistically different. Conclusion: From normal to SCD and RCF, they appear a tendency to decline in memory and language functions, and there are significant differences between subjects with RCF and normal controls.
