Abstract:Objective: To compare the performance of mini mental state examination (MMSE) and Chinese version of brief assessment of impaired cognition (BASIC) in the cognitive assessment of patients with stroke, so as to provide theoretical reference for clinical use. Methods: A total of 97 patients with stroke hospitalized in The First People's Hospital of Changzhou from May 2020 to January 2021 were selected as the stroke group, and another 40 healthy individuals matched with age, sex and education level were selected as the control group. All subjects were assessed by trained rehabilitation physicians for MMSE and BASIC, and the results were compared and analyzed. Results: ①Compared with the control group, the scores of MMSE and BASIC in the stroke group decreased significantly, indicating that the cognitive function of patients with stroke was significantly impaired. ②The results of MMSE and BASIC in the stroke group were positively correlated (r=0.662, P=0.000). ③Linear correlation suggested that age was negatively correlated with MMSE (r=-0.324, P=0.001) and BASIC (r=-0.401, P=0.000), while education years were positively correlated with MMSE (r=0.349, P=0.000) and BASIC (r=0.378, P=0.000). However, multiple linear regression showed that the results of MMSE were not affected by age.④MMSE and BASIC had no significant ceiling and floor effects.⑤Kappa analysis showed that the consistency of the two scales in screening for cognitive dysfunction in stroke patients was fair (Kappa=0.286, P=0.005). ⑥The receiver operating characteristic curve showed that there was no significant difference in the areas under the curve between MMSE and BASIC. The best cut-off values of MMSE and BASIC were 27.5 and 20.5, respectively. Conclusion: BASIC scale has low attenuation effect and short operation time, which can be used as an early rapid screening tool for cognitive dysfunction after stroke. However, it is necessary to further improve its assessment accuracy and pay attention to the selection of the assessment population.
