Research progress of cognition, sleep and plasma biomarkers in patients with cerebral small vessel disease

Abstract:

In recent years, with the improvement and popularization of neuroimaging technology, more and more cases of cerebral small vessel disease (CSVD) have been correctly identified, and it has become a common disease among the elderly. CSVD can cause a series of problems threatening patients'health, especially cognitive impairment. However, due to the lack of prominent early symptoms and lagging imaging examination, there is still a lack of effective means to identify such diseases as soon as possible. This paper expounds the imaging classification of CSVD and its characteristic cognitive function changes, and discusses its relationship between sleep and plasma biomarkers, so as to provide a strong basis for early clinical differential diagnosis and individualized treatment.