Quantitative electroencephalogram analysis in patients with semantic dementia

Abstract:

Objective: To explore the characteristics of quantitative analysis of EEG in patients with semantic dementia (SD). Methods: Nine SD patients and 30 normal controls sex and age matched were selected for electroencephalogram (EEG) examination. The results of the EEG data were visually scored and quantitatively analyzed. The relative power ratio of (δ+θ) / (α+β) (DTABR) at the whole brain, left and right frontal, anterior-temporal, middle-posterior temporal, center, parietal and occipital area was measured respectively. The value of DTABR and the result of visual analysis were compared between the two groups, and the symmetry of EEG activity of bilateral brain in SD patients was observed simultaneously. Results: Compared with the normal control group, the slowwave activity and the DTABR of SD patients were significantly increased (P<0.01). The DTABR on the left brain side was significantly higher than that on the right side in SD patients, especially on the anterior-temporal area (P<0.05). Conclusion: Quantitative EEG can reflect the changes in brain function of SD patients and provide objective quantitative indicators for exploring the electrophysiological mechanism of SD.