Research progress of Schwann cells and repair of spinal cord injury

Abstract:

Remyelination disorder after spinal cord injury（SCI） is the main cause of neurological dysfunction in patients. As the glial cells of the peripheral nervous system（PNS），Schwann cells（SC） are involved in the formation and repair of myelin sheath. However，more and more studies have shown that SC can be observed at the injured site after SCI. In this paper，we have reviewed the cell source，repair mechanism and regulatory factors of SC in the process of SCI repair.