Research progress of glial cells in the pathogenesis of vascular cognitive impairment

Abstract:

Vascular cognitive impairment（VCI） is a kind of disease caused by cerebrovascular diseases and other related risk factors，ranging from mild cognitive impairment to dementia. The pathological features of VCI mainly include white matter lesions，demyelination and neuroinflammation. Glial cells are the most numerous cells in the brain，and play an important role in maintaining the normal function of the central nervous system. Recent studies have found that glial cells play an important role in the pathogenesis of vascular cognitive impairment. Exploring the role of glial cells will help improve our understanding of VCI and provide new ideas for the prevention and treatment of the disease.