Abstract:Chronic spontaneous urticaria (CSU) is a common allergic skin disease in clinical practice. Its pathogenesis is complex and has not been fully elucidated. According to the popular theory of helper T lymphocyte 1 (Th1) /Th2 cytokine imbalance in recent years, Th2 cytokines can directly or indirectly induce allergic diseases, and their abnormal secretion is closely related to the occurrence, development, and prognosis of CSU. In addition, in recent years, Th17 cytokines have also attracted the attention of researchers, and more and more evidence has shown that it plays an important role in CSU. The drug treatment for related cytokines has also made unprecedented progress. Therefore, this paper reviews the roles of Th2 and Th17-related cytokines in the occurrence and development of CSU, and provides references for subsequent research and treatment.
