On the effect of individualized pulmonary protective ventilation on general anesthesia pulmonary ventilation in patients undergoing craniocerebral surgery

Abstract:

Objective: To investigate the effect of individualized pulmonary protective ventilation on general anesthesia pulmonary ventilation in patients undergoing craniocerebral surgery. Methods: Fifty-four patients admitted to Huzhou Central Hospital for craniocerebral surgery from July 2018 to July 2019 were selected as the study objects. They were divided into the conventional group (n=27) and the individualized group (n=27) randomly. The conventional group was given traditional volumetric control mechanical ventilation, and the individualized group was given individualized pulmonary protective ventilation by positive end expiratory pressure (PEEP) . Blood gas analysis, mean arterial pressure, pulmonary dynamic compliance and airway platform pressure were detected and compared before anesthesia induction (T₀), after skin incision (T₁), mechanical ventilation for 1 h (T₂), for 2 h (T₃), and tracheal extubation for 30 min (T₄), and chest CT one day after surgery and the occurrence of pulmonary complications within seven days after surgery were recorded. Results: Compared with the conventional group, the oxygenation index at T₁, T₂and T₃and the lung dynamic compliance in the individualized group were significantly higher (P<0.05) . At the same time, the airway platform pressure at T₁, T₂and T₃was significantly lower than that in the conventional group (P<0.05) . Conclusion: Compared with conventional ventilation, individualized pulmonary protective ventilation can improve the intraoperative oxygenation index and dynamic compliance of lung, and reduce the airway platform pressure during mechanical ventilation, which is safe and effective.