Abstract:Objective: To investigate and analyze the detection rate and influencing factors of non-alcoholic fatty liver disease (NAFLD) in adult male healthy subjects in Southeast Chongqing, and to provide reference for the prevention and treatment of NAFLD. Methods: A total of 16 792 men who underwent physical examination in the physical examination center of a grade three hospital in Southeast Chongqing were selected as the research objects, and their data were retrospectively analyzed. The detection rate of NAFLD was calculated and the related risk factors of NAFLD were analyzed by univariate and multivariate Logistic regression. Results: Among the subjects, 3 441 were NAFLD patients, with the detection rate of 20.5%, and the detection rate was highest in 51 to 60 years old group (29.4%). The mean levels of body mass index (BMI), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and alanine transaminase (ALT) in NAFLD group were significantly higher than those in non-NAFLD group (P<0.01) and high density lipoprotein cholesterol (HDL-C) was significantly lower than that in non-NAFLD group (P<0.01). Multivariate Logistic regression analysis showed that age, BMI, hypertension, triglyceride and ALT were independent risk factors for NAFLD (P<0.01). Conclusion: The detection rate of nonalcoholic fatty liver disease in male population in Southeast Chongqing is relatively high, with the highest onset among 51-60 years old group. Ultrasound screening of NAFLD should be focused on those with obesity, hypertension, and rised triglyceride and ALT levels for the prevention and treatment of NAFLD.
