Abstract:Objective: To improve clinician’s understanding of dengue fever. Methods: The clinical data of 201 dengue fever patients admitted to the First People’s Hospital of Liangjiang New Area from August to October, 2019 were retrospectively analyzed. Chi-square was used for discontinuous variables, and t test was used for continuous variables. Results: Among 201 dengue fever patients, 97 (48.26%) were male, and 104 (51.74%) were female. The number of them over 60 years old was 40 (19.90%). The common manifestations included fever (99.00%), feeble (85.07%), and myalgia soreness (85.57%). Laboratory examination showed that most patients had neutropenia (90.53%), thrombocytopenia (70.00%), and liver function damage (30.00%). The incidence of thrombocytopenia was higher in elderly patients than that in young and middle-aged patients (66.67% vs. 85.25%, P=0.04). In addition, the incidence of liver damage in the elderly patients was higher (50.00% vs. 25.64%, P=0.01), with more serious damage. Etiological examination showed that all patients’ dengue virus RNA (DENA-RNA) were positive, the locally infected patients were genotype 1, and two imported patients were genotype 2 and genotype 3. All patients were treated by symptomatic support to prevent complications, most patients with mild symptoms and with good prognosis. Conclusion: In 2019, the epidemic of dengue fever in our district is mainly genotype 1, with fever, fatigue, myalgia soreness as typical clinical features, accompanied by neutropenia, thrombocytopenia and liver function damage, especially in elderly patients, which should be paid great attention to.