Advances in clinical diagnosis of paraneoplastic neurological syndrome

Abstract:

Paraneoplastic neurological syndromes（PNS） are a group of rare immune-mediated diseases in which tumors affect the nervous system through remote effects. Clinical symptoms are diverse and usually accompanied by specific neural antibodies. In 2021，the international expert group revised the 2004 version of the PNS diagnostic criteria，developed a new clinical scoring system， and highlighted the relationship between “phenotype-antibody-tumor”. This review aims to summarize the progress of the diagnosis of PNS， with a special focus on the new diagnostic criteria.