Study on the diagnostic value of inflammation score system in preeclampsia

Abstract:

Objective To study the changes and clinical significance of neutrophil-lymphocyte ratio（NLR），platelet-lymphocyte ratio （PLR） in peripheral blood，mean platelet volume（MPV） and platelet hematocrit（PCT） in preeclampsia.Methods The peripheral blood routine data and clinical data of 160 pregnant women with preeclampsia were retrospectively studied，including 80 cases of mild preeclampsia（MPE） and 80 cases of severe preeclampsia（SPE）. The control group included 80 normal pregnant women visited our department during the same period. The NLR，PLR，MPV，and PCT were compared among SPE，MPE and the control group.Results There were significant differences in neutrophil，PLR，MPV，PCT among the three groups（P<0.05），but no significant difference in lymphocyte（P>0.05）. There was significant difference in neutrophils between the MPE group and the control group（P<0.05）. There were significant differences in neutrophil，platelet，PLR，MPV and PCT between SPE group and control group（P<0.05），and there were significant differences in neutrophil，platelet，PLR，MPV and PCT between SPE group and MPE group（P<0.05）.Conclusion The detection of PLR，MPV and PCT in peripheral blood has certain value in the diagnosis of preeclampsia，and it can also reflect the severity of preeclampsia.