Feasibility and safety of hysteroscopic tissue removal system in treatment of interstitial ectopic pregnancy

Abstract:

Objective To investigate the feasibility and safety of hysteroscopic tissue removal system in the treatment of interstitial ectopic pregnancy.Methods Related clinical data were collected from 16 patients with unruptured interstitial ectopic pregnancy who were admitted to Department of Gynecology，Jiangxi Maternal and Child Health Hospital，from April 2019 to April 2022 and were treated by the hysteroscopic tissue resection system，and a preoperative analysis was performed for preoperative blood β-human chorionic gonadotropin（β-HCG），ultrasound findings，time of operation，intraoperative blood loss，and time for blood β-HCG to return to normal after surgery.Results The 16 patients with unruptured interstitial ectopic pregnancy had a preoperative blood β-HCG level of 830-31 153 mIU/mL，with a mean value of （8 643.561±1 752.000） mIU/mL，and pregnancy tissue on ultrasound had a maximum size of 33 cm×28 cm and a minimum size of 11 cm×10 cm. All patients had a confirmed diagnosis of interstitial ectopic pregnancy after microscopic examination，and hysteroscopic tissue resection system was used to remove the lesions of interstitial pregnancy，among whom 2 patients were converted to laparoscopy. The mean time of operation was 34（20，92） minutes，and the mean volume of intraoperative blood loss was 46.6（10，250） mL. The surgical process was smooth with no obvious complications. The patients had a mean hospital stay of 2 days and a time of （22.00±5.11） days for blood β-HCG to return to normal after surgery. Ultrasound examination at 1 month after surgery showed no residue of pregnancy tissue，and 5 patients became pregnant successfully during follow-up for half a year.Conclusion The hysteroscopic tissue resection system can preserve organ integrity in the treatment of unruptured interstitial ectopic pregnancy.