Clinical analysis of 158 children with ovarian cysts

Abstract:

Objective To improve clinicians’ knowledge of ovarian cysts in children by analyzing the clinical data of 158 children with ovarian cysts.Methods The clinical data of 158 children with ovarian cysts admitted to the outpatient department of Chengdu Women’s and Children’s Central Hospital from September 2019 to September 2022 were collected and divided into three groups according to age（0-1 year，>1-8 years，and >8-16 years）. The clinical characteristics of these patients were analyzed.Results Most of the neonatal and infant ovarian cysts were identified incidentally. Most of the clinical symptoms，including breast development（81.3%） and vaginal bleeding（25.0%），were found in girls aged >1-8 years. Irregular menstruation（45.6%） and abdominal pain（33.3%） were the most common symptoms in girls aged above 8 years. Most of the patients were diagnosed with simple ovarian cysts，but six patients were found to have ovarian tumors. Ovarian torsion was found in 7 cases. Most of the ovarian cysts resolved spontaneously during the follow-up，but some recurred in the children. Central precocious puberty was observed in two children during the follow-up. The surgical intervention rate was 8.9%.Conclusion For most of the girls，no intervention is needed due to their diagnosis with simple cysts； however，some of them may have underlying disease causes or complications such as ovarian tumors，McCune-Albright syndrome，Van Wyk-Grumbach syndrome，central precocious puberty，and ovarian torsion. Hence，these patients should be evaluated carefully and treated with multidisciplinary approaches.