Abstract:Arginine vasopressin (AVP) is a hormone synthesized from the hypothalamus in response to increased plasma osmotic pressure and decreased blood volume, which influences glucolipid metabolism by binding to AVP receptors. Recent studies show that Copeptin, co-secreted with AVP in equimolar amounts, is considered stabilized, sensitive and not bioactive surrogate marker of AVP. Elevated plasma levels of Copeptin are essentially associated with diabetes, diabetic complications, obesity, insulin resistance, hyper-tension, hyperlipidemia, non-alcoholic fatty liver disease and other metabolic diseases. Therefore, exploring the relationship between Copeptin and metabolic diseases actively will contribute to the early diagnosis of related diseases.
